Drosophila Omi, a mitochondrial-localized IAP antagonist and proapoptotic serine protease

Although essential in mammals, in flies the importance of mitochondrial outer membrane permeabilization for apoptosis remains highly controversial. Herein, we demonstrate that Drosophila Omi (dOmi), a fly homologue of the serine protease Omi/HtrA2, is a developmentally regulated mitochondrial interm...

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Detalhes bibliográficos
Main Authors: Challa, Madhavi, Malladi, Srinivas, Pellock, Brett J, Dresnek, Douglas, Varadarajan, Shankar, Yin, Y Whitney, White, Kristin, Bratton, Shawn B
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2007
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1914093/
https://ncbi.nlm.nih.gov/pubmed/17557079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601745
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