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The Wilms' Tumor Suppressor Protein WT1 Is Processed by the Serine Protease HtrA2/Omi

The Wilms' tumor suppressor protein WT1 functions as a transcriptional regulator of genes controlling growth, apoptosis, and differentiation. It has become clear that WT1 can act as an oncogene in many tumors, primarily through the inhibition of apoptosis. Here, we identify the serine protease...

詳細記述

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書誌詳細
主要な著者: Hartkamp, Jörg, Carpenter, Brian, Roberts, Stefan G.E.
フォーマット: Artigo
言語:Inglês
出版事項: Cell Press 2010
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2815029/
https://ncbi.nlm.nih.gov/pubmed/20122399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2009.12.023
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