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The Wilms' Tumor Suppressor Protein WT1 Is Processed by the Serine Protease HtrA2/Omi
The Wilms' tumor suppressor protein WT1 functions as a transcriptional regulator of genes controlling growth, apoptosis, and differentiation. It has become clear that WT1 can act as an oncogene in many tumors, primarily through the inhibition of apoptosis. Here, we identify the serine protease...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Cell Press
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2815029/ https://ncbi.nlm.nih.gov/pubmed/20122399 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2009.12.023 |
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