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Drosophila Omi, a mitochondrial-localized IAP antagonist and proapoptotic serine protease

Although essential in mammals, in flies the importance of mitochondrial outer membrane permeabilization for apoptosis remains highly controversial. Herein, we demonstrate that Drosophila Omi (dOmi), a fly homologue of the serine protease Omi/HtrA2, is a developmentally regulated mitochondrial interm...

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Bibliografiske detaljer
Main Authors: Challa, Madhavi, Malladi, Srinivas, Pellock, Brett J, Dresnek, Douglas, Varadarajan, Shankar, Yin, Y Whitney, White, Kristin, Bratton, Shawn B
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2007
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1914093/
https://ncbi.nlm.nih.gov/pubmed/17557079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601745
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