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Tumour prevention by a single antibody domain targeting the interaction of signal transduction proteins with RAS
Many disease-related processes occur via protein complexes that are considered undruggable with small molecules. An example is RAS, which is frequently mutated in cancer and contributes to initiation and maintenance of the disease by constitutive signal transduction through protein interaction with...
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| Главные авторы: | , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Nature Publishing Group
2007
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1914092/ https://ncbi.nlm.nih.gov/pubmed/17568777 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601744 |
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