Control of specificity and magnitude of NF-κB and STAT1-mediated gene activation through PIASy and PIAS1 cooperation

NF-κB and STATs regulate multiple cellular processes through the transcriptional activation of genes with diversified functions. Although the molecular mechanisms that can turn on/off the overall NF-κB/STAT signaling have been extensively studied, how NF-κB/STAT-target genes can be differentially re...

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Bibliographic Details
Main Authors: Tahk, Samuel, Liu, Bin, Chernishof, Vasili, Wong, Kelly A., Wu, Hong, Shuai, Ke
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2007
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1913887/
https://ncbi.nlm.nih.gov/pubmed/17606919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0701877104
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