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Inhibition of Stat1-mediated gene activation by PIAS1

STAT (signal transducer and activator of transcription) proteins are latent cytoplasmic transcription factors that become activated by tyrosine phosphorylation in response to cytokine stimulation. Tyrosine phosphorylated STATs dimerize and translocate into the nucleus to activate specific genes. Dif...

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Detalhes bibliográficos
Main Authors: Liu, Bin, Liao, Jiayu, Rao, Xiaoping, Kushner, Steven A., Chung, Chan D., Chang, David D., Shuai, Ke
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 1998
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC27945/
https://ncbi.nlm.nih.gov/pubmed/9724754
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