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The zinc finger protein Gfi-1 can enhance STAT3 signaling by interacting with the STAT3 inhibitor PIAS3

STAT factors act as signal transducers of cytokine receptors and transcriptionally activate specific target genes. The recently discovered protein PIAS3 binds directly to STAT3 and blocks transcriptional activation. Here, we present experimental evidence implementing the zinc finger protein Gfi-1 as...

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Bibliografiske detaljer
Udgivet i:EMBO J
Principais autores: Rödel, Bernd, Tavassoli, Kamiab, Karsunky, Holger, Schmidt, Thorsten, Bachmann, Malte, Schaper, Fred, Heinrich, Peter, Shuai, Ke, Elsässer, Hans Peter, Möröy, Tarik
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2000
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC305799/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11060035/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/19.21.5845
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