The zinc finger protein Gfi-1 can enhance STAT3 signaling by interacting with the STAT3 inhibitor PIAS3

STAT factors act as signal transducers of cytokine receptors and transcriptionally activate specific target genes. The recently discovered protein PIAS3 binds directly to STAT3 and blocks transcriptional activation. Here, we present experimental evidence implementing the zinc finger protein Gfi-1 as...

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Main Authors: Rödel, Bernd, Tavassoli, Kamiab, Karsunky, Holger, Schmidt, Thorsten, Bachmann, Malte, Schaper, Fred, Heinrich, Peter, Shuai, Ke, Elsässer, Hans Peter, Möröy, Tarik
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2000
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Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC305799/
https://ncbi.nlm.nih.gov/pubmed/11060035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/19.21.5845
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