Overexpression of PDGF-BB decreases colorectal and pancreatic cancer growth by increasing tumor pericyte content

We hypothesized that overexpression of PDGF-BB in colorectal cancer (CRC) and pancreatic cancer cells would result in increased pericyte coverage of ECs in vivo, rendering the tumor vasculature more resistant to antiangiogenic therapy. We stably transfected the cDNA for the PDGF-B into HT-29 human C...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: McCarty, Marya F., Somcio, Ray J., Stoeltzing, Oliver, Wey, Jane, Fan, Fan, Liu, Wenbiao, Bucana, Corazon, Ellis, Lee M.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Clinical Investigation 2007
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1913488/
https://ncbi.nlm.nih.gov/pubmed/17641778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI31334
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares