Roles of rapH and rapG in Positive Regulation of Rapamycin Biosynthesis in Streptomyces hygroscopicus

Rapamycin is an important macrocyclic polyketide produced by Streptomyces hygroscopicus and showing immunosuppressive, antifungal, and antitumor activities as well as displaying anti-inflammatory and neuroregenerative properties. The immense pharmacological potential of rapamycin has led to the prod...

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Bibliografske podrobnosti
Main Authors: Kuščer, Enej, Coates, Nigel, Challis, Iain, Gregory, Matt, Wilkinson, Barrie, Sheridan, Rose, Petković, Hrvoje
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2007
Teme:
Gene Regulation
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1913445/
https://ncbi.nlm.nih.gov/pubmed/17468238
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.00129-07
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