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The variable domain of nonassembled Ig light chains determines both their half-life and binding to the chaperone BiP

Not much is known about the features that determine the biological stability of a molecule retained in the endoplasmic reticulum (ER). Ig light (L) chains that are not secreted in the absence of Ig heavy (H) chain expression bind to the ER chaperone BiP as partially folded molecules until they are d...

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Bibliografske podrobnosti
Main Authors: Skowronek, Markus H., Hendershot, Linda M., Haas, Ingrid G.
Format: Artigo
Jezik:Inglês
Izdano: The National Academy of Sciences 1998
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC19100/
https://ncbi.nlm.nih.gov/pubmed/9465057
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