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The variable domain of nonassembled Ig light chains determines both their half-life and binding to the chaperone BiP

Not much is known about the features that determine the biological stability of a molecule retained in the endoplasmic reticulum (ER). Ig light (L) chains that are not secreted in the absence of Ig heavy (H) chain expression bind to the ER chaperone BiP as partially folded molecules until they are d...

詳細記述

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書誌詳細
主要な著者: Skowronek, Markus H., Hendershot, Linda M., Haas, Ingrid G.
フォーマット: Artigo
言語:Inglês
出版事項: The National Academy of Sciences 1998
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC19100/
https://ncbi.nlm.nih.gov/pubmed/9465057
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