Dissociation from BiP and Retrotranslocation of Unassembled Immunoglobulin Light Chains Are Tightly Coupled to Proteasome Activity
Unassembled immunoglobulin light chains expressed by the mouse plasmacytoma cell line NS1 (κ(NS1)) are degraded in vivo with a half-life of 50–60 min in a way that closely resembles endoplasmic reticulum (ER)-associated degradation (Knittler et al., 1995). Here we show that the peptide aldehydes MG1...
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| 出版年: | Mol Biol Cell |
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| 主要な著者: | , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society for Cell Biology
2000
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC14769/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10637303/ https://ncbi.nlm.nih.govhttps://doi.org/10.1091/mbc.11.1.217 |
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