Dissociation from BiP and Retrotranslocation of Unassembled Immunoglobulin Light Chains Are Tightly Coupled to Proteasome Activity
Unassembled immunoglobulin light chains expressed by the mouse plasmacytoma cell line NS1 (κ(NS1)) are degraded in vivo with a half-life of 50–60 min in a way that closely resembles endoplasmic reticulum (ER)-associated degradation (Knittler et al., 1995). Here we show that the peptide aldehydes MG1...
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| Yayımlandı: | Mol Biol Cell |
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| Asıl Yazarlar: | , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
American Society for Cell Biology
2000
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC14769/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10637303/ https://ncbi.nlm.nih.govhttps://doi.org/10.1091/mbc.11.1.217 |
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