RNase H domain of Moloney murine leukemia virus reverse transcriptase retains activity but requires the polymerase domain for specificity.

The reverse transcriptase-associated RNase H activity of Moloney murine leukemia virus specifically cleaves within the polypurine tract region of the viral genome to generate the primer for plus-strand DNA synthesis and removes the tRNA primer after minus-strand initiation by preferentially cleaving...

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Bibliografski detalji

Izdano u:	J Virol
Glavni autori:	Schultz, S J, Champoux, J J
Format:	Artigo
Jezik:	Inglês
Izdano:	American Society for Microbiology (ASM) 1996
Teme:	Research Article
Online pristup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC190956/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8970988/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.70.12.8630-8638.1996
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