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Increased Expression Of Ctla-4 (Cd152) By T And B Lymphocytes In Wegener'S Granulomatosis
CTLA-4 (CD152) is a surface molecule of activated T cells with sequence homology to CD28. Both molecules bind to the same ligands, B7.1 (CD80) and B7.2 (CD86) but have antagonistic functions. While CD28 is an important costimulator, CTLA-4 has an essential inhibitory function in maintaining the home...
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| Glavni autori: | , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Blackwell Science Inc
2001
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1906160/ https://ncbi.nlm.nih.gov/pubmed/11678911 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2249.2001.01575.x |
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