Increased Expression Of Ctla-4 (Cd152) By T And B Lymphocytes In Wegener'S Granulomatosis

CTLA-4 (CD152) is a surface molecule of activated T cells with sequence homology to CD28. Both molecules bind to the same ligands, B7.1 (CD80) and B7.2 (CD86) but have antagonistic functions. While CD28 is an important costimulator, CTLA-4 has an essential inhibitory function in maintaining the home...

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Detalhes bibliográficos
Main Authors: Steiner, K, Moosig, F, Csernok, E, Selleng, K, Gross, W L, Fleischer, B, BröKer, B M
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2001
Assuntos:
Immunity to Infection
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1906160/
https://ncbi.nlm.nih.gov/pubmed/11678911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2249.2001.01575.x
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