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Structural basis for conserved complement factor-like function in the antimalarial protein TEP1

Thioester-containing proteins (TEPs) are a major component of the innate immune response of insects to invasion by bacteria and protozoa. TEPs form a distinct clade of a superfamily that includes the pan-protease inhibitors α(2)-macroglobulins and vertebrate complement factors. The essential feature...

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Detalhes bibliográficos
Main Authors: Baxter, Richard H. G., Chang, Chung-I, Chelliah, Yogarany, Blandin, Stéphanie, Levashina, Elena A., Deisenhofer, Johann
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2007
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1905922/
https://ncbi.nlm.nih.gov/pubmed/17606907
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0704967104
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