Structure of the ectodomain of Drosophila peptidoglycan-recognition protein LCa suggests a molecular mechanism for pattern recognition

The peptidoglycan-recognition protein LCa (PGRP-LCa) is a transmembrane receptor required for activation of the Drosophila immune deficiency pathway by monomeric Gram-negative peptidoglycan. We have determined the crystal structure of the ectodomain of PGRP-LCa at 2.5-Å resolution and found two uniq...

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Detaylı Bibliyografya
Asıl Yazarlar: Chang, Chung-I, Ihara, Kentaro, Chelliah, Yogarany, Mengin-Lecreulx, Dominique, Wakatsuki, Soichi, Deisenhofer, Johann
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2005
Konular:
Biological Sciences
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC1174924/
https://ncbi.nlm.nih.gov/pubmed/16006509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0504547102
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