The Drosophila peptidoglycan-recognition protein LF interacts with peptidoglycan-recognition protein LC to downregulate the Imd pathway

The peptidoglycan (PGN)-recognition protein LF (PGRP-LF) is a specific negative regulator of the immune deficiency (Imd) pathway in Drosophila. We determine the crystal structure of the two PGRP domains constituting the ectodomain of PGRP-LF at 1.72 and 1.94 Å resolution. The structures show that th...

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Detalhes bibliográficos
Main Authors: Basbous, Nada, Coste, Franck, Leone, Philippe, Vincentelli, Renaud, Royet, Julien, Kellenberger, Christine, Roussel, Alain
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2011
Assuntos:
Scientific Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3077246/
https://ncbi.nlm.nih.gov/pubmed/21372849
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/embor.2011.19
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