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A heterodimeric complex of the LRR proteins LRIM1 and APL1C regulates complement-like immunity in Anopheles gambiae

The leucine-rich repeat (LRR) proteins LRIM1 and APL1C control the function of the complement-like protein TEP1 in Anopheles mosquitoes. The molecular structure of LRIM1 and APL1C and the basis of their interaction with TEP1 represent a new type of innate immune complex. The LRIM1/APL1C complex spec...

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Detalhes bibliográficos
Main Authors: Baxter, Richard H. G., Steinert, Stefanie, Chelliah, Yogarany, Volohonsky, Gloria, Levashina, Elena A., Deisenhofer, Johann
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2947905/
https://ncbi.nlm.nih.gov/pubmed/20826443
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1010575107
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