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Molecular Basis for Genetic Resistance of Anopheles gambiae to Plasmodium: Structural Analysis of TEP1 Susceptible and Resistant Alleles

Thioester-containing protein 1 (TEP1) is a central component in the innate immune response of Anopheles gambiae to Plasmodium infection. Two classes of TEP1 alleles, TEP1*S and TEP1*R, are found in both laboratory strains and wild isolates, related by a greater or lesser susceptibility, respectively...

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Detalhes bibliográficos
Main Authors: Le, Binh V., Williams, Marni, Logarajah, Shankar, Baxter, Richard H. G.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3464232/
https://ncbi.nlm.nih.gov/pubmed/23055931
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1002958
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