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Postnatal Overexpression of the CT GalNAc Transferase Inhibits Muscular Dystrophy in mdx mice without Altering Muscle Growth or Neuromuscular Development: Evidence for a Utrophin-Independent Mechanism

Overexpression of the cytotoxic T cell (CT) GalNAc transferase (Galgt2) in the skeletal muscles of transgenic mdx mice inhibits the development of muscular dystrophy. The profound effect of Galgt2 on muscular dystrophy in transgenic mice, where overexpression is begins from embryonic stages, is comp...

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Autori principali: Xu, Rui, Camboni, Marybeth, Martin, Paul T.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2007
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1905823/
https://ncbi.nlm.nih.gov/pubmed/17300937
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nmd.2006.12.004
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