Tumour necrosis factor (TNF) production by T cell receptor-primed T lymphocytes is a target for low dose methotrexate in rheumatoid arthritis

Methotrexate (MTX) is an effective immunosuppressive agent in various chronic inflammatory diseases such as rheumatoid arthritis (RA). However, its mechanisms of action are only partially understood. In this study, we assessed the effects of MTX on the differentiation of peripheral blood (PB) CD4(+)...

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Bibliographische Detailangaben
Hauptverfasser: Hildner, K, Finotto, S, Becker, C, Schlaak, J, Schirmacher, P, Galle, P R, Märker-Hermann, E, Neurath, M F
Format: Artigo
Sprache:Inglês
Veröffentlicht: Blackwell Science Inc 1999
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Original Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1905404/
https://ncbi.nlm.nih.gov/pubmed/10540171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2249.1999.01022.x
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