Methotrexate specifically modulates cytokine production by T cells and macrophages in murine collagen-induced arthritis (CIA): a mechanism for methotrexate-mediated immunosuppression

Immunosuppressive therapy with methotrexate (MTX) has been established as effective treatment for patients with rheumatoid arthritis. To analyse the therapeutic potential and mechanisms of action of MTX, we determined serum cytokine levels and cytokine production by splenic T cells and macrophages i...

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Detaylı Bibliyografya
Asıl Yazarlar: Neurath, M F, Hildner, K, Becker, C, Schlaak, J F, Barbulescu, K, Germann, T, Schmitt, E, Schirmacher, P, Haralambous, S, Pasparakis, M, Meyer Zum BÜschenfelde, K-H, Kollias, G, MÄrker-Hermann, E
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Blackwell Science Inc 1999
Konular:
Original Articles
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC1905174/
https://ncbi.nlm.nih.gov/pubmed/9933419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2249.1999.00753.x
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