Tumour necrosis factor (TNF) production by T cell receptor-primed T lymphocytes is a target for low dose methotrexate in rheumatoid arthritis

Methotrexate (MTX) is an effective immunosuppressive agent in various chronic inflammatory diseases such as rheumatoid arthritis (RA). However, its mechanisms of action are only partially understood. In this study, we assessed the effects of MTX on the differentiation of peripheral blood (PB) CD4(+)...

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Bibliografiske detaljer
Main Authors:	Hildner, K, Finotto, S, Becker, C, Schlaak, J, Schirmacher, P, Galle, P R, Märker-Hermann, E, Neurath, M F
Format:	Artigo
Sprog:	Inglês
Udgivet:	Blackwell Science Inc 1999
Fag:	Original Articles
Online adgang:	https://ncbi.nlm.nih.gov/pmc/articles/PMC1905404/ https://ncbi.nlm.nih.gov/pubmed/10540171 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2249.1999.01022.x
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Tumour necrosis factor (TNF) production by T cell receptor-primed T lymphocytes is a target for low dose methotrexate in rheumatoid arthritis

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