Decreased CD40 ligand induction in CD4 T cells and dysregulated IL-12 production during HIV infection

During HIV infection various cytokines are overproduced in early stages, whereas in advanced disease cytokines of the T helper 1 type (e.g. interferon-gamma (IFN-γ)) are selectively deficient. During antigenic stimulation, the production of type-1 cytokines is enhanced by IL-12, secreted by antigen-...

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Detalhes bibliográficos
Main Authors: Vanham, G, Penne, L, Devalck, J, Kestens, L, Colebunders, R, Bosmans, E, Thielemans, K, Ceuppens, J L
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 1999
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1905331/
https://ncbi.nlm.nih.gov/pubmed/10444266
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2249.1999.00987.x
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