Superantigen activation of CD4(+) and CD8(+) T cells from HIV-infected subjects: role of costimulatory molecules and antigen-presenting cells (APC)

T cell receptor (TCR) triggering via superantigens induces decreased proliferative responses and increased apoptosis in T cells from HIV-infected patients compared with controls. Our aim was to delineate the role of intrinsic T cell defects, of APC dysfunction and of cytokines and costimulatory sign...

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Bibliografiske detaljer
Main Authors: Vingerhoets, J, Dohlsten, M, Penne, G, Colebunders, R, Sansom, D, Bosmans, E, Kestens, L, Vanham, G
Format: Artigo
Sprog:Inglês
Udgivet: Blackwell Science Inc 1998
Fag:
Original Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1904857/
https://ncbi.nlm.nih.gov/pubmed/9472656
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2249.1998.00465.x
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