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Recombinant α-chains of type IV collagen demonstrate that the amino terminal of the Goodpasture autoantigen is crucial for antibody recognition
Goodpasture's disease, an autoimmune disorder causing severe glomerulonephritis and pulmonary haemorrhage, is characterized by antibodies to the glomerular basement membrane (GBM). The principal target antigen has been identified as the carboxyl terminal non-collagenous (NC1) domain of the α3-c...
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Egile Nagusiak: | , , , |
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Formatua: | Artigo |
Hizkuntza: | Inglês |
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Blackwell Publishing Ltd
1998
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Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1905021/ https://ncbi.nlm.nih.gov/pubmed/9697978 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2249.1998.00623.x |
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