Molecular cloning of the human Goodpasture antigen demonstrates it to be the alpha 3 chain of type IV collagen.

To characterize the autoantigen of Goodpasture's (anti-glomerular basement membrane) disease, a molecule of 26-kD reactive with autoantibodies from patients' sera was purified from collagenase digests of sheep glomerular basement membrane. Short internal amino acid sequences were obtained...

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Détails bibliographiques
Auteurs principaux: Turner, N, Mason, P J, Brown, R, Fox, M, Povey, S, Rees, A, Pusey, C D
Format: Artigo
Langue:Inglês
Publié: 1992
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC442892/
https://ncbi.nlm.nih.gov/pubmed/1737849
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