Molecular cloning of the human Goodpasture antigen demonstrates it to be the alpha 3 chain of type IV collagen.

To characterize the autoantigen of Goodpasture's (anti-glomerular basement membrane) disease, a molecule of 26-kD reactive with autoantibodies from patients' sera was purified from collagenase digests of sheep glomerular basement membrane. Short internal amino acid sequences were obtained after tryp...

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Pubblicato in:	J Clin Invest
Autori principali:	Turner, N, Mason, P J, Brown, R, Fox, M, Povey, S, Rees, A, Pusey, C D
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Clinical Investigation 1992
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC442892/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1737849/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI115625
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