Somatic hypermutation of immunoglobulin genes is independent of the Bloom's syndrome DNA helicase

Immunoglobulin gene somatic mutation leads to antibody affinity maturation through the introduction of multiple point mutations in the antigen binding site. No genes have as yet been identified that participate in this process. Bloom's syndrome (BS) is a chromosomal breakage disorder with a mut...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Sack, S Z, Liu, Y, German, J, Green, N S
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Blackwell Science Inc 1998
Pynciau:
Original Articles
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC1904964/
https://ncbi.nlm.nih.gov/pubmed/9649187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2249.1998.00575.x
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