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The in vivo induction of lymphocyte apoptosis in MRL-lpr/lpr mice treated with FTY720
The in vitro treatment of lpr thymocytes with FTY720 resulted in a dose-dependent reduction in cell viability due to apoptosis. In order to study the effect of FTY720 in vivo, lpr mice received an oral daily dose of 1 mg/kg FTY720 for 14 days, beginning at 16 weeks of age which was when the animals...
Αποθηκεύτηκε σε:
| Κύριοι συγγραφείς: | , , , , , , |
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| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
Blackwell Science Inc
1997
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1904563/ https://ncbi.nlm.nih.gov/pubmed/9010264 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2249.1997.d01-885.x |
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