Cyclophilin A is required for an early step in the life cycle of human immunodeficiency virus type 1 before the initiation of reverse transcription.

Cyclophilin A (CyPA) is incorporated into human immunodeficiency virus type 1 (HIV-1) virions via contact with the Gag polyprotein. Genetic or pharmacologic disruption of CyPA incorporation causes a quantitative reduction in virion infectivity with no discernible effects on virion assembly or on end...

Full description

Bibliographic Details

Published in:	J Virol
Main Authors:	Braaten, D, Franke, E K, Luban, J
Format:	Artigo
Language:	Inglês
Published:	American Society for Microbiology (ASM) 1996
Subjects:	Research Article
Online Access:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC190230/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8648689/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.70.6.3551-3560.1996
Tags:	Add Tag No Tags, Be the first to tag this record!