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Cyclophilin A is required for an early step in the life cycle of human immunodeficiency virus type 1 before the initiation of reverse transcription.

Cyclophilin A (CyPA) is incorporated into human immunodeficiency virus type 1 (HIV-1) virions via contact with the Gag polyprotein. Genetic or pharmacologic disruption of CyPA incorporation causes a quantitative reduction in virion infectivity with no discernible effects on virion assembly or on end...

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Bibliografische gegevens
Gepubliceerd in:J Virol
Hoofdauteurs: Braaten, D, Franke, E K, Luban, J
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology (ASM) 1996
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC190230/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8648689/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.70.6.3551-3560.1996
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