Cyclophilin A is required for an early step in the life cycle of human immunodeficiency virus type 1 before the initiation of reverse transcription.

Cyclophilin A (CyPA) is incorporated into human immunodeficiency virus type 1 (HIV-1) virions via contact with the Gag polyprotein. Genetic or pharmacologic disruption of CyPA incorporation causes a quantitative reduction in virion infectivity with no discernible effects on virion assembly or on end...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Braaten, D, Franke, E K, Luban, J
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1996
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC190230/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8648689/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.70.6.3551-3560.1996
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