Mutational analysis of the human immunodeficiency virus type 2 (HIV-2) genome in relation to HIV-1 and simian immunodeficiency virus SIV (AGM).

We constructed an infectious molecular clone of the human immunodeficiency virus type 2 (HIV-2) and generated nine frameshift mutants corresponding to nine open reading frames identified so far. Three structural (gag, pol, env) and two regulative (tat, rev) gene mutants were not infectious, whereas...

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Detalhes bibliográficos
Main Authors: Shibata, R, Miura, T, Hayami, M, Ogawa, K, Sakai, H, Kiyomasu, T, Ishimoto, A, Adachi, A
Formato: Artigo
Idioma:Inglês
Publicado em: 1990
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC249168/
https://ncbi.nlm.nih.gov/pubmed/2296082
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