Suppression of cell transformation by the cyclin-dependent kinase inhibitor p57(KIP2 )requires binding to proliferating cell nuclear antigen
Proper control of the mammalian cell cycle requires the function of cyclin-dependent kinase (CDK) inhibitors. The p21 family currently includes three distinct genes, p21, p27(Kip1), and p57(Kip2), that share a common N-terminal domain for binding to and inhibiting the kinase activity of CDK-cyclin c...
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| Опубликовано в:: | Proc Natl Acad Sci U S A |
|---|---|
| Главные авторы: | , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
National Academy of Sciences
1998
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC19016/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9465025/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.4.1392 |
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