Farnesyl transferase inhibitors cause enhanced mitotic sensitivity to taxol and epothilones

An important class of cellular proteins, which includes members of the p21ras family, undergoes posttranslational farnesylation, a modification required for their partition to membranes. Specific farnesyl transferase inhibitors (FTIs) have been developed that selectively inhibit the processing of th...

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Detaylı Bibliyografya
Asıl Yazarlar: Moasser, Mark M., Sepp-Lorenzino, Laura, Kohl, Nancy E., Oliff, Allen, Balog, Aaron, Su, Dai-Shi, Danishefsky, Samuel J., Rosen, Neal
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: The National Academy of Sciences 1998
Konular:
Biological Sciences
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC19006/
https://ncbi.nlm.nih.gov/pubmed/9465021
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