Multifunctional Human Immunodeficiency Virus (HIV) Gag-Specific CD8(+) T-Cell Responses in Rectal Mucosa and Peripheral Blood Mononuclear Cells during Chronic HIV Type 1 Infection

The intestinal tract is a lymphocyte-rich site that undergoes severe depletion of memory CD4(+) T cells within days of simian immunodeficiency virus or human immunodeficiency virus type 1 (HIV-1) infection. An ensuing influx of virus-specific CD8(+) T cells, which persist throughout the chronic phas...

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Detalhes bibliográficos
Main Authors: Critchfield, J. William, Lemongello, Donna, Walker, Digna H., Garcia, Juan C., Asmuth, David M., Pollard, Richard B., Shacklett, Barbara L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2007
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1900284/
https://ncbi.nlm.nih.gov/pubmed/17344302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02535-06
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