Herpes simplex ICP27 mutant viruses exhibit reduced expression of specific DNA replication genes.

Herpes simplex virus type 1 mutants with certain lesions in the ICP27 gene show a 5- to 10-fold reduction in viral DNA synthesis. To determine how ICP27 promotes amplification of viral DNA, we examined the synthesis, accumulation, and stability of the essential viral replication proteins and steady-...

Täydet tiedot

Bibliografiset tiedot

Julkaisussa:	J Virol
Päätekijät:	Uprichard, S L, Knipe, D M
Aineistotyyppi:	Artigo
Kieli:	Inglês
Julkaistu:	American Society for Microbiology (ASM) 1996
Aiheet:	Research Article
Linkit:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC190026/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8627723/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.70.3.1969-1980.1996
Tagit:	Lisää tagi Ei tageja, Lisää ensimmäinen tagi!