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Epitope-Dependent Avidity Thresholds for Cytotoxic T-Lymphocyte Clearance of Virus-Infected Cells

Cytotoxic T lymphocytes (CTLs) are crucial for immune control of viral infections. “Functional avidity,” defined by the sensitizing dose of exogenously added epitope yielding half-maximal CTL triggering against uninfected target cells (SD(50)), has been utilized extensively as a measure of antiviral...

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Main Authors: Bennett, Michael S., Ng, Hwee L., Dagarag, Mirabelle, Ali, Ayub, Yang, Otto O.
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Microbiology 2007
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1900201/
https://ncbi.nlm.nih.gov/pubmed/17329324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02362-06
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