Developmental Changes in Histone macroH2A1-Mediated Gene Regulation

macroH2A histone variants have been implicated to function in gene silencing by several studies, including ones showing a preferential association of macroH2A on the inactive X chromosome. To examine macroH2A function in vivo, we knocked out macroH2A1. macroH2A1 knockout mice are viable and fertile....

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Bibliografiske detaljer
Main Authors: Changolkar, Lakshmi N., Costanzi, Carl, Leu, N. Adrian, Chen, Dannee, McLaughlin, K. John, Pehrson, John R.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2007
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Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1899912/
https://ncbi.nlm.nih.gov/pubmed/17242180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.02334-06
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