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macroH2A1-Dependent Silencing of Endogenous Murine Leukemia Viruses

We show that macroH2A1 histone variants are important for repressing the expression of endogenous murine leukemia viruses (MLVs) in mouse liver. Intact MLV proviruses and proviruses with deletions in env were nearly silent in normal mouse liver and showed substantial derepression in macroH2A1 knocko...

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Autori principali: Changolkar, Lakshmi N., Singh, Geetika, Pehrson, John R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology (ASM) 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2268408/
https://ncbi.nlm.nih.gov/pubmed/18195046
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01362-07
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