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macroH2A1-Dependent Silencing of Endogenous Murine Leukemia Viruses

We show that macroH2A1 histone variants are important for repressing the expression of endogenous murine leukemia viruses (MLVs) in mouse liver. Intact MLV proviruses and proviruses with deletions in env were nearly silent in normal mouse liver and showed substantial derepression in macroH2A1 knocko...

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Detalhes bibliográficos
Main Authors: Changolkar, Lakshmi N., Singh, Geetika, Pehrson, John R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2268408/
https://ncbi.nlm.nih.gov/pubmed/18195046
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01362-07
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