Prostate Cancer-Associated Membrane Type 1-Matrix Metalloproteinase : A Pivotal Role in Bone Response and Intraosseous Tumor Growth

Membrane type 1-matrix metalloproteinase (MT1-MMP) is a major mediator of collagen I degradation. In human samples, we show that prostate cancer cells in skeletal metastases consistently express abundant MT1-MMP protein. Because prostate cancer bone metastasis requires remodeling of the collagen-ric...

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Autors principals: Bonfil, R. Daniel, Dong, Zhong, Trindade Filho, J. Carlos, Sabbota, Aaron, Osenkowski, Pamela, Nabha, Sanaa, Yamamoto, Hamilto, Chinni, Sreenivasa R., Zhao, Huiren, Mobashery, Shahriar, Vessella, Robert L., Fridman, Rafael, Cher, Michael L.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Investigative Pathology 2007
Matèries:
Regular Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1899437/
https://ncbi.nlm.nih.gov/pubmed/17525276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2007.060720
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