Cleavage at the stem region releases an active ectodomain of the membrane type 1 matrix metalloproteinase

MT1-MMP (membrane type 1 matrix metalloproteinase) is a membrane-anchored MMP that can be shed to the extracellular milieu. In the present study we report the primary structure and activity of the major soluble form of MT1-MMP. MS analysis of the purified 50-kDa soluble MT1-MMP form shows that the e...

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Detalhes bibliográficos
Main Authors: Toth, Marta, Osenkowski, Pamela, Hesek, Dusan, Brown, Stephen, Meroueh, Samy, Sakr, Wael, Mobashery, Shahriar, Fridman, Rafael
Formato: Artigo
Idioma:Inglês
Publicado em: Portland Press Ltd. 2005
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1134979/
https://ncbi.nlm.nih.gov/pubmed/15560752
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20041324
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