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Thermodynamics of Interactions of Vancomycin and Synthetic Surrogates of Bacterial Cell Wall

[Image: see text] Glycopeptide antibiotics, including vancomycin, form complexes via a set of five hydrogen bonds with the acyl-l-Lys-d-Ala-d-Ala portion of the peptidyl stems of the bacterial cell wall peptidoglycan. This complexation deprives the organism from the ability to cross-link peptidyl st...

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Main Authors: Rekharsky, Mikhail, Hesek, Dusan, Lee, Mijoon, Meroueh, Samy O., Inoue, Yoshihisa, Mobashery, Shahriar
Formato: Artigo
Idioma:Inglês
Publicado: 2006
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3297417/
https://ncbi.nlm.nih.gov/pubmed/16771477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja061828+
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