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Thermodynamics of Interactions of Vancomycin and Synthetic Surrogates of Bacterial Cell Wall
[Image: see text] Glycopeptide antibiotics, including vancomycin, form complexes via a set of five hydrogen bonds with the acyl-l-Lys-d-Ala-d-Ala portion of the peptidyl stems of the bacterial cell wall peptidoglycan. This complexation deprives the organism from the ability to cross-link peptidyl st...
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| Hauptverfasser: | , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2006
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3297417/ https://ncbi.nlm.nih.gov/pubmed/16771477 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja061828+ |
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