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CXCL12/CXCR4 Transactivates HER2 in Lipid Rafts of Prostate Cancer Cells and Promotes Growth of Metastatic Deposits in Bone

Chemokines and their receptors function in migration and homing of cells to target tissues. Recent evidence suggests that cancer cells use a chemokine receptor axis for metastasis formation at secondary sites. Previously, we showed that binding of the chemokine CXCL12 to its receptor CXCR4 mediated...

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Autores principales: Chinni, Sreenivasa R., Yamamoto, Hamilto, Dong, Zhong, Sabbota, Aaron, Bonfil, R. Daniel, Cher, Michael L.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2008
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3842603/
https://ncbi.nlm.nih.gov/pubmed/18337451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-07-0117
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