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Susceptibility of Hermansky-Pudlak Mice to Bleomycin-Induced Type II Cell Apoptosis and Fibrosis

Pulmonary inflammation, abnormalities in type II cell and macrophage morphology, and pulmonary fibrosis are features of Hermansky-Pudlak Syndrome (HPS), a recessive disorder associated with intracellular trafficking defects. We have previously reported that “Pearl” (HPS2) and “Pale Ear” (HPS1) mouse...

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Detalhes bibliográficos
Main Authors: Young, Lisa R., Pasula, Rajamouli, Gulleman, Peter M., Deutsch, Gail H., McCormack, Francis X.
Formato: Artigo
Idioma:Inglês
Publicado em: American Thoracic Society 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1899346/
https://ncbi.nlm.nih.gov/pubmed/17363777
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2006-0469OC
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